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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF2
All Species:
11.21
Human Site:
S278
Identified Species:
22.42
UniProt:
Q99496
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99496
NP_009143.1
336
37655
S278
E
L
R
S
K
G
E
S
N
Q
M
N
L
D
T
Chimpanzee
Pan troglodytes
XP_514057
377
41465
R317
K
D
D
S
A
Q
T
R
Y
I
K
T
S
G
N
Rhesus Macaque
Macaca mulatta
Q8WMN5
377
39081
P319
G
G
D
G
P
E
E
P
A
L
P
S
L
E
G
Dog
Lupus familis
XP_859868
264
29237
N207
L
R
S
K
G
E
S
N
Q
M
N
L
D
T
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQJ4
336
37605
S278
E
L
R
S
K
G
E
S
N
Q
M
N
L
D
T
Rat
Rattus norvegicus
Q4KLY4
308
34224
S251
Q
T
R
Y
I
K
T
S
G
N
A
T
V
D
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422295
336
37573
S278
E
L
R
S
K
G
E
S
N
Q
M
N
L
D
T
Frog
Xenopus laevis
Q66J69
344
38348
A284
E
E
V
L
R
G
E
A
E
G
V
T
L
G
E
Zebra Danio
Brachydanio rerio
Q803I4
336
37521
A278
E
M
R
K
N
G
E
A
S
P
I
N
V
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VB08
435
47237
T363
I
K
T
T
A
N
A
T
V
D
H
L
S
K
Y
Honey Bee
Apis mellifera
XP_393984
403
44539
R322
A
L
K
E
N
S
I
R
Y
I
K
T
T
A
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788976
652
73333
N585
S
Q
S
S
S
N
Q
N
E
G
G
C
G
E
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.9
53.8
77.9
N.A.
99.6
90.4
N.A.
N.A.
97.9
71.2
89.2
N.A.
42.9
51.3
N.A.
20.2
Protein Similarity:
100
81.1
66
78.2
N.A.
100
91
N.A.
N.A.
99.1
80.2
93.4
N.A.
56
65.7
N.A.
33.5
P-Site Identity:
100
6.6
13.3
0
N.A.
100
20
N.A.
N.A.
100
26.6
33.3
N.A.
0
6.6
N.A.
6.6
P-Site Similarity:
100
13.3
26.6
6.6
N.A.
100
33.3
N.A.
N.A.
100
46.6
73.3
N.A.
13.3
13.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
17
0
9
17
9
0
9
0
0
9
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
0
9
17
0
0
0
0
0
0
9
0
0
9
34
0
% D
% Glu:
42
9
0
9
0
17
50
0
17
0
0
0
0
25
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% F
% Gly:
9
9
0
9
9
42
0
0
9
17
9
0
9
17
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
9
% H
% Ile:
9
0
0
0
9
0
9
0
0
17
9
0
0
0
0
% I
% Lys:
9
9
9
17
25
9
0
0
0
0
17
0
0
9
0
% K
% Leu:
9
34
0
9
0
0
0
0
0
9
0
17
42
0
0
% L
% Met:
0
9
0
0
0
0
0
0
0
9
25
0
0
0
0
% M
% Asn:
0
0
0
0
17
17
0
17
25
9
9
34
0
0
17
% N
% Pro:
0
0
0
0
9
0
0
9
0
9
9
0
0
0
0
% P
% Gln:
9
9
0
0
0
9
9
0
9
25
0
0
0
0
0
% Q
% Arg:
0
9
42
0
9
0
0
17
0
0
0
0
0
0
0
% R
% Ser:
9
0
17
42
9
9
9
34
9
0
0
9
17
0
0
% S
% Thr:
0
9
9
9
0
0
17
9
0
0
0
34
9
9
25
% T
% Val:
0
0
9
0
0
0
0
0
9
0
9
0
17
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
0
17
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _